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  Home > Categories > Parkinson & Alzheimer > Selegiline Hcl  

Selegiline Hcl (Zelapar / Eldepryl)

Description

Selegiline is a selective irreversible MAO-B inhibitor used for the treatment of early-stage Parkinson's disease and senile dementia. It acts by inhibiting the activity of monoamine oxidase which prevents the breakdown of monoamine neurotransmitters and increases their availability. It has been approved by the Food and Drug Administration (FDA) in February 28, 2006 to treat major depression using a transdermal patch. It is also used in veterinary medicine to treat the symptoms of Cushing's disease and cognitive dysfunction. It is available in market under brand names Zelapar and Eldepryl in the form of tablet.

Bookmark Manufacturer : Intas
Brand : Zelapar / Eldepryl (Selgin)
Average Delivery Time : 10 to 14 working days
 
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Quantity Strength Price/Pill Price (USD $)  
30 Pills 0.25 mg $0.37 $11.00 Add to Cart
60 Pills 0.5 mg $0.30 $18.00 Add to Cart
90 Pills 0.5 mg $0.29 $26.00 Add to Cart
What is it used for (Indication) ?
It is used for the treatment of early-stage Parkinson's disease, depression and senile dementia. It is also used in veterinary medicine to treat the symptoms of cushing's disease and cognitive dysfunction.
How it works (Mechanism)?
It is a selective irreversible MAO-B inhibitor, acts by inhibiting the activity of monoamine oxidase which prevents the breakdown of monoamine neurotransmitters and increases their availability.
What is Parkinson's disease, Depression & Dementia (disease) ?
Parkinson's disease : It is a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills, speech and other functions.

Depression : It is a mental disorder characterized by low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities.

Dementia : It a condition of deprived mind, is a serious loss of cognitive ability in a previously-unimpaired person than normal aging.
How to take this medicine (Administration & Dosage) ?
1. It should be taken 5mg twice daily, maximum dose is 10mg once daily.
2. If dose is missed, take it as soon as possible. Skip the dose if it is almost on the time for next dose.
Side effects of medicine
It may show some common side effects which include dizziness, dry mouth, constipation, muscle pain, rash, nausea and difficulty in falling or staying asleep.
Interaction with other medicines
It may interact with :
  1. Antidepressants like fluoxetine and citalopram
  2. Drugs used for blood pressure or nitric drugs.
  3. Insulin and oral antidiabetic drugs.
  4. MAO inhibitors like furazolidone, linezolid, moclobemide and phenelzine.
  5. Other drugs like brimonidine,bupropion, buspirone and carbamazepine.
Contraindications (Who should avoid this)
  1. In patients with a known hypersensitivity to this drug.
  2. For use with meperidine and other opioids.
Storage conditions
1. Keep away from light and moisture.
2. Store at room temperature between 20˚ to 25˚C (68˚ to 77˚F).
Why should you buy from Rx2gostore
Rx2gostore is an online licensed pharmacy providing you quality medicines with very reasonable rates. Our medicines are affordable because we buy bulk medicines directly from manufacturer.
Generic vs Brand
Generic and branded both medicines are same, contains same ingredient, uses, effects and quality. Branded medicine is costly because it is a patent drug of manufacturer which includes cost of research, marketing, promotion and taxes while generic medicines are cheap because it saves all above cost.
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